Tyrosine

Tyrosine

SCHEMBL7795418

CC(C)C[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.61
FOLH1 Q04609 1/20 0.46
ACE P12821 5/20 0.45
MME P08473 1/20 0.45
CPA1 P15085 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
PTGS1 P23219 2/20 0.45
ALPI P09923 1/20 0.45
PKM P14618 1/20 0.45
XIAP P98170 1/20 0.45
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
EGFR P00533 1/20 0.43
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ALOX15 P16050 1/20 0.43
HTR2A P28223 1/20 0.43
PTGS2 P35354 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL18249988 1.00 SLC7A5 (0.61) SLC7A5FOLH1ACEMMECPA1
Tyrosine SCHEMBL27347200 1.00 SLC7A5 (0.61) SLC7A5FOLH1ACEMMECPA1
Tyrosine SCHEMBL27866450 0.95 SLC7A5 (0.56) SLC7A5FOLH1ACEMMECPA1
Tyrosine SCHEMBL3442322 0.94 SLC7A5 (0.55) SLC7A5FOLH1ACEMMECPA1
Tyrosine SCHEMBL1537442 0.93 SLC7A5 (0.71) SLC7A5ACEMMECPA1ACE2
Tyrosine SCHEMBL1537436 0.93 SLC7A5 (0.71) SLC7A5ACEMMECPA1ACE2
Tyrosine SCHEMBL14562522 0.93 SLC7A5 (0.71) SLC7A5ACEMMECPA1ACE2
Tyrosine SCHEMBL14247975 0.93 SLC7A5 (0.71) SLC7A5ACEMMECPA1ACE2
Tyrosine SCHEMBL3131438 0.93 SLC7A5 (0.53) SLC7A5ACEPTGS1ALPIPKM
Tyrosine SCHEMBL3131428 0.93 SLC7A5 (0.53) SLC7A5ACEPTGS1ALPIPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3298025-A1 NEW AMINO ACID SEQUENCES WITH MICROBICIDAL ACTIVITY DERIVED FROM NAJA ATRA CARDIOTOXIN 1 (CTX-1) Università degli Studi di Parma (IT) 2018-03-28 EP disclosed
WO-2016184855-A1 NEW AMINO ACID SEQUENCES WITH MICROBICIDAL ACTIVITY DERIVED FROM NAJA ATRA CARDIOTOXIN 1 (CTX-1) Università degli Studi di Parma (IT) 2016-11-24 WO disclosed
EP-1152769-A1 YEAST CELL WALL PEPTIDES AND ANTIBODIES THERETO THE UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2001-11-14 EP disclosed
WO-2000048620-A1 YEAST CELL WALL PEPTIDES AND ANTIBODIES THERETO UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2000-08-24 WO disclosed