Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28441615 | 0.84 | GSTP1 (0.50) | HDAC4HDAC2HDAC8GSTP1HSD17B1 | |
| SCHEMBL30128001 | 0.84 | GSTP1 (0.50) | HDAC4HDAC2HDAC8GSTP1HSD17B1 | |
| SCHEMBL19664922 | 0.84 | TDP1 (0.42) | HDAC4HDAC2HDAC8PTGS2KDM4E | |
| SCHEMBL4005844 | 0.84 | GSTP1 (0.53) | HDAC4HDAC2HDAC8GSTP1HSD17B1 | |
| Biphenyl SCHEMBL4005991 | 0.82 | GSTP1 (0.52) | HDAC4HDAC2HDAC8GSTP1HSD17B1 | |
| SCHEMBL19305535 | 0.82 | TDP1 (0.41) | HDAC4HDAC2HDAC8PTGS2KDM4E | |
| SCHEMBL1768199 | 0.79 | TDP1 (0.41) | HDAC4HDAC2HDAC8PTGS2KDM4E | |
| SCHEMBL4007611 | 0.78 | GSTP1 (0.55) | HDAC4HDAC2HDAC8GSTP1HSD17B1 | |
| SCHEMBL7795653 | 0.78 | MAPT (0.43) | HDAC8CYP2C9TSHRCYP2C19KDM4E | |
| SCHEMBL31158582 | 0.78 | MAPT (0.43) | HDAC8CYP2C9TSHRCYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8245663-A | — | — | None | — | — | JP | disclosed |
| EP-0731105-B1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL CO (JP) | 2001-12-05 | — | — | EP | disclosed |
| US-5621129-A | Optically active tertiary phosphine compound, transition metal complex comprising the same as ligand and process for preparing optically active organic silicon compound using said transition metal complex | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| JP-H08245663-A | PHOSPHINE COMPOUND, TRANSITION METAL COMPLEX CONTAINING THE COMPOUND AS LIGAND AND ITS USE | SUMITOMO CHEM CO LTD | 1996-09-24 | — | — | JP | disclosed |
| EP-0731105-A1 | Optically active tertiary phosphine compounds, transition metal complexes comprising the same as ligands and process for preparing optically active organic silicon compounds using said transition metal complexes | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-09-11 | — | — | EP | disclosed |