Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.81 |
| ▸ | HTR2A | P28223 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | GMNN | O75496 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.81 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
| ▸ | THPO | P40225 | 1/20 | 0.81 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794028 | 0.94 | SLC6A4 (0.84) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| SCHEMBL29363403 | 0.90 | SLC6A4 (1.00) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| SCHEMBL7793847 | 0.90 | SLC6A4 (1.00) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| SCHEMBL7793808 | 0.88 | SLC6A4 (0.76) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| SCHEMBL7793813 | 0.88 | SLC6A4 (0.76) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| Phosphoric Acid SCHEMBL8111167 | 0.86 | SLC6A4 (0.93) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| SCHEMBL7796909 | 0.86 | SLC6A4 (0.79) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| SCHEMBL8112179 | 0.85 | SLC6A4 (0.75) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| SCHEMBL8117843 | 0.85 | SLC6A4 (0.78) | SLC6A4HTR2AKDM4EGMNNALDH1A1 | |
| SCHEMBL7797321 | 0.84 | SLC6A4 (0.73) | SLC6A4HTR2AKDM4EGMNNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010053783-A1 | Central nervous system disorders | FAIRHURST JOHN (GB) | 2001-12-20 | — | — | US | disclosed |
| EP-0854146-B1 | Substituted 4-(6-fluoro-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders | LILLY CO ELI (GB) | 2000-03-15 | — | — | EP | disclosed |
| EP-0854146-A1 | Substituted 4-(6-fluoro-[1H]-indol-3-yl)-1,2,3,6-tetrahydropyridine for the treatment of CNS-disorders | ELI LILLY AND COMPANY LIMITED (GB) | 1998-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053783-A1 | Central nervous system disorders | CNR1, PMP22, CNR2 | SLC6A4 126/4885HTR2A 332/4885KDM4E 4138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.