SCHEMBL7795714

SCHEMBL7795714

CCCCOc1cc(OCCCC2CCCNC2)cc2c1-c1c(OCCCC3CCCNC3)cccc1C2=O

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 12/20 0.42
ACP1 P24666 4/20 0.41
KCNA3 P22001 1/20 0.39
TLR7 Q9NYK1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7786481 0.96 HTR2A (0.41) NPY1RACP1KCNA3
SCHEMBL7794815 0.96 HTR2A (0.41) NPY1RACP1KCNA3
SCHEMBL7786088 0.94 NPY1R (0.40) NPY1RACP1KCNA3
SCHEMBL7792449 0.94 KCNA3 (0.41) NPY1RKCNA3
SCHEMBL7792139 0.93 ACP1 (0.41) NPY1RACP1KCNA3
SCHEMBL7794705 0.92 NPY1R (0.41) NPY1RACP1KCNA3TLR7
SCHEMBL7794760 0.91 ACP1 (0.42) NPY1RACP1KCNA3
SCHEMBL7786391 0.90 HTR2A (0.42) NPY1RKCNA3
SCHEMBL7786238 0.90 HTR2A (0.42) NPY1RKCNA3
SCHEMBL7794782 0.89 KCNA3 (0.41) NPY1RKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0906268-B1 ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS AVENTIS PHARMA INC (US) 2001-11-28 EP disclosed
US-6004959-A HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS HOECHST MARION ROUSSEL, INC. (US) 1999-12-21 US disclosed