Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795848 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7802483 | 0.89 | KDM4E (0.40) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7802480 | 0.89 | KDM4E (0.40) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7802593 | 0.85 | HSD17B10 (0.50) | SMN1; SMN2ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7802590 | 0.85 | HSD17B10 (0.50) | SMN1; SMN2ALDH1A1GAAKMT2AMEN1 | |
| SCHEMBL7801758 | 0.84 | MAPT (0.39) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7801761 | 0.84 | MAPT (0.39) | SMN1; SMN2ALDH1A1HPGDGAAKMT2A | |
| SCHEMBL7805464 | 0.84 | ABL1 (0.46) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL7805468 | 0.84 | ABL1 (0.46) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL7801742 | 0.84 | KDM4E (0.47) | ALDH1A1GAAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |