Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.64 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786287 | 0.95 | MAPT (0.71) | MAPTKMT2ACHRNA7ALKADORA2A | |
| SCHEMBL7792632 | 0.94 | MAPT (0.56) | MAPTKMT2ACHRNA7TTRL3MBTL1 | |
| SCHEMBL7792554 | 0.92 | MAPT (0.67) | MAPTKMT2ACHRNA7ADORA2AADORA1 | |
| SCHEMBL7796349 | 0.92 | MAPT (0.67) | MAPTKMT2ACHRNA7ALKADORA2A | |
| SCHEMBL7786303 | 0.91 | MAPT (0.61) | MAPTKMT2ACHRNA7ALKADORA2A | |
| SCHEMBL7792326 | 0.91 | MAPT (0.67) | MAPTKMT2ACHRNA7ADORA2AADORA1 | |
| SCHEMBL7795949 | 0.89 | MAPT (0.62) | MAPTKMT2ACHRNA7ADORA2AADORA1 | |
| SCHEMBL27512821 | 0.89 | MAPT (0.62) | MAPTKMT2ACHRNA7ALKADORA2A | |
| SCHEMBL28742032 | 0.88 | MAPT (0.57) | MAPTKMT2ACHRNA7ALK | |
| SCHEMBL7796272 | 0.87 | MAPT (0.60) | MAPTKMT2ACHRNA7ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |