Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795720 | 0.97 | TTR (0.39) | TTRMAPTL3MBTL1PTPRCSLC6A2 | |
| SCHEMBL7792427 | 0.93 | MAPT (0.36) | TTRMAPTL3MBTL1MEN1KMT2A | |
| SCHEMBL7786028 | 0.90 | KMT2A (0.38) | MAPTL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7786314 | 0.90 | SLC6A2 (0.36) | TTRPTPRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7791964 | 0.89 | TTR (0.39) | TTRPTPRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7792122 | 0.89 | SLC6A2 (0.43) | MAPTL3MBTL1PTPRCSLC6A2SLC6A4 | |
| SCHEMBL7786401 | 0.88 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3PDCD1LG2CD274 | |
| SCHEMBL7795914 | 0.88 | TTR (0.43) | TTRMAPTPTPRCSLC6A2SLC6A4 | |
| SCHEMBL7792036 | 0.88 | TTR (0.39) | TTRMAPTL3MBTL1PTPRCSLC6A2 | |
| SCHEMBL7791850 | 0.87 | TTR (0.39) | TTRPTPRCSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |