Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.39 |
| ▸ | ACP1 | P24666 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 3/20 | 0.35 |
| ▸ | JUND | P17535 | 1/20 | 0.35 |
| ▸ | FOSB | P53539 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7786255 | 0.96 | KCNA3 (0.41) | ALDH1A1CYP1A2CYP3A4KCNA3ACP1 | |
| SCHEMBL7786097 | 0.94 | EED (0.44) | ALDH1A1CYP1A2CYP3A4KCNA3ACP1 | |
| SCHEMBL7792388 | 0.91 | ACP1 (0.41) | KCNA3ACP1MEN1KMT2AEED | |
| SCHEMBL7794760 | 0.90 | ACP1 (0.42) | KCNA3ACP1EEDNPY1R | |
| SCHEMBL7786391 | 0.87 | HTR2A (0.42) | KCNA3ELANENPY1RHTR2AHTR2C | |
| SCHEMBL7792449 | 0.87 | KCNA3 (0.41) | ALDH1A1KCNA3ELANEMEN1KMT2A | |
| SCHEMBL7794782 | 0.87 | KCNA3 (0.41) | KCNA3NPY1RHTR2AHTR2CHTR2B | |
| SCHEMBL7786173 | 0.87 | HTR2A (0.39) | KCNA3ACP1NPY1RHTR2AHTR2C | |
| SCHEMBL7786238 | 0.87 | HTR2A (0.42) | KCNA3ELANENPY1RHTR2AHTR2C | |
| SCHEMBL7792232 | 0.85 | MEN1 (0.42) | ALDH1A1KCNA3ACP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0906268-B1 | ALKYLOXYAMINO SUBSTITUTED FLUORENONES AND THEIR USE AS PROTEIN KINASE C INHIBITORS | AVENTIS PHARMA INC (US) | 2001-11-28 | — | — | EP | disclosed |
| US-6004959-A | HYPOTENSIVE, ANTITUMOR, ANTIINFLAMMATORY AND ANTIASTHMATIC AGENTS; ANGIOGENESIS AND ALVEOLAR MACROPHAGE ACTIVATION INHIBITORS | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |