Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126027 | 0.97 | ATM (0.45) | ATMHDAC1HDAC8HDAC6KDM1A | |
| SCHEMBL18805040 | 0.97 | ATM (0.45) | ATMHDAC1HDAC8HDAC6KDM1A | |
| SCHEMBL353495 | 0.95 | ESR2 (0.47) | ATMHDAC1HDAC8HDAC6KDM1A | |
| Benzene SCHEMBL26615260 | 0.93 | SLC18A3 (0.46) | ATMHDAC1HDAC8HDAC6LMNA | |
| SCHEMBL15906653 | 0.91 | NOTUM (0.47) | ATMNOTUMLMNAHTTHSP90AA1 | |
| SCHEMBL1066184 | 0.89 | KDM1A (0.48) | ATMKDM1AESR2TDP1MAP1LC3B | |
| SCHEMBL18161913 | 0.89 | KDM1A (0.48) | ATMKDM1AESR2TDP1MAP1LC3B | |
| Bicarbonate SCHEMBL9321721 | 0.87 | HAO1 (0.51) | ATMHDAC1HDAC8HDAC6HTT | |
| SCHEMBL26154104 | 0.87 | PARP10 (0.50) | KDM1AHAO1SLC6A2HTR2ASLC6A4 | |
| Ammonia Solution, Strong SCHEMBL22408764 | 0.86 | KDM1A (0.46) | ATMKDM1AESR2MAP1LC3BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593214-B | Method for synthesizing N-benzyl-N-cyclopropyl-1H-pyrazole-4-formamide derivative | 拜耳作物科学股份公司 | 2018-05-29 | — | — | CN | claimed |
| US-8372854-B2 | Pyrrolo[2,3-D]pyrimidine compounds | PFIZER INC. (US) | 2013-02-12 | — | — | US | claimed |
| EP-2513114-A1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | Pfizer Inc. (US) | 2012-10-24 | — | — | EP | claimed |
| US-20110294826-A1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2011-12-01 | — | — | US | claimed |
| WO-2011075334-A1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | PFIZER INC. (US) | 2011-06-23 | — | — | WO | claimed |
| WO-2010131147-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131146-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| WO-2010131145-A1 | CYCLOBUTENEDIONE DERIVATIVES | PFIZER LIMITED (GB) | 2010-11-18 | — | — | WO | claimed |
| US-12100809-B2 | Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2024-09-24 | — | — | US | disclosed |
| EP-3784669-B1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMA (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230312587-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | VERTEX PHARMACEUTICALS INCORPORATED | 2023-10-05 | — | — | US | disclosed |
| US-11572364-B2 | Pteridinone compounds and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-02-07 | — | — | US | disclosed |
| US-20220149436-A1 | NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-05-12 | — | — | US | disclosed |
| US-11283107-B2 | Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-03-22 | — | — | US | disclosed |
| WO-2008061781-A1 | THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURO-DEGENERATIVE DISEASES | NV REMYND (BE) | 2008-05-29 | — | — | WO | disclosed |
| US-7271184-B2 | Acyclic and cyclic guanidine- and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides | NOVARTIS ANIMAL HEALTH US, INC. (US) | 2007-09-18 | — | — | US | disclosed |
| CN-1177823-C | Pesticides | ��˹��ŵ�� | 2004-12-01 | — | — | CN | disclosed |
| US-6759407-B2 | A VETERINARY MEDICINE FOR CONTROLLING PARASITES AND PESTS ON ANIMALS | NOVARTIS ANIMAL HEALTH US, INC. | 2004-07-06 | — | — | US | disclosed |
| EP-1131292-A2 | ACYCLIC AND CYCLIC GUANIDINE- AND ACETAMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES, ESP. AS PARASITICIDES | Novartis AG (CH) | 2001-09-12 | — | — | EP | disclosed |
| WO-2000029378-A2 | ACYCLIC AND CYCLIC GUANIDINE- AND ACETAMIDINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES, ESP. AS PARASITICIDES | NOVARTIS AG (CH) | 2000-05-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572364-B2 | Pteridinone compounds and uses thereof | DPYD, PKD1, TYMP | ATM 1497/4885HDAC1 1240/4885HDAC8 896/4885 |
| US-20110294826-A1 | PYRROLO[2,3-D]PYRIMIDINE COMPOUNDS | JAK3, JAK1, JAK2 | ATM 781/4885HDAC1 2627/4885HDAC8 3039/4885 |
| US-20230312587-A1 | PTERIDINONE COMPOUNDS AND USES THEREOF | DPYD, PKD1, TYMP | ATM 1497/4885HDAC1 1240/4885HDAC8 896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.