Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.43 |
| ▸ | TDO2 | P48775 | 8/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 2/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14380217 | 0.86 | MEN1 (0.43) | IDO1TDO2TSHRSCN1ASCN2A | |
| SCHEMBL127629 | 0.75 | IDO1 (0.46) | IDO1TDO2DPP4TSHRF2 | |
| Methane SCHEMBL29089947 | 0.73 | IDO1 (0.44) | IDO1TDO2DPP4TSHRF2 | |
| Ammonia Solution, Strong SCHEMBL7282272 | 0.73 | IDO1 (0.44) | IDO1TDO2DPP4TSHRF2 | |
| Water SCHEMBL11878861 | 0.73 | IDO1 (0.44) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL7099520 | 0.72 | TSHR (0.50) | IDO1TDO2DPP4TSHRF2 | |
| SCHEMBL907605 | 0.72 | HCAR2 (0.42) | DPP4F2ADRA2AADRA2BLMNA | |
| SCHEMBL20527054 | 0.72 | DPP4 (0.38) | DPP4TSHRF2HTR2AHRH1 | |
| SCHEMBL14380354 | 0.72 | SLC6A4 (0.31) | IDO1TDO2SLC6A4SLC6A3HRH4 | |
| SCHEMBL14380352 | 0.71 | SCN1A (0.55) | TSHRSCN1ASCN2ASCN3ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983222-B1 | PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS | NYMOX CORP (CA) | 2007-11-28 | — | — | EP | disclosed |
| EP-0808849-B1 | Process for the production of ethylenic polymers | SHOWA DENKO KK (JP) | 2001-12-19 | — | — | EP | disclosed |
| US-6011127-A | CATALYST COMPRISING A CHROMIUM COMPOUND, AN ALUMOXANE AND AN ORGANOMETALLIC ALKOXIDE AND/OR ORGANOMETALLIC SILOXIDE AND A CARRIER SUPPORTING THEREON THESE COMPOUNDS. | SHOWA DENKO K.K. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0574258-B1 | Process for producing alpha-olefin polymers | MITSUBISHI CHEM CORP (JP) | 1998-01-14 | — | — | EP | disclosed |
| EP-0808849-A1 | Process for the production of ethylenic polymers | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1997-11-26 | — | — | EP | disclosed |
| EP-0574258-A2 | Process for producing alpha-olefin polymers | MITSUBISHI CHEMICAL CORPORATION (JP) | 1993-12-15 | — | — | EP | disclosed |
| US-3946131-A | Glass fibers coated with silicon containing aminimide compounds | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1976-03-23 | — | — | US | disclosed |