Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | F11 | P03951 | 2/20 | 0.44 |
| ▸ | TPSB2 | P20231 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24527656 | 0.87 | PTGS1 (0.50) | PTGS1ALOX5KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9526801 | 0.83 | PTGS1 (0.53) | PTGS1ALOX5KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7088219 | 0.82 | KMT2A (0.70) | PTGS1ALOX5KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7087851 | 0.82 | KMT2A (0.70) | PTGS1ALOX5KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL6922512 | 0.82 | KMT2A (0.70) | PTGS1ALOX5KMT2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7091370 | 0.81 | KMT2A (0.68) | PTGS1ALOX5KMT2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7092750 | 0.81 | KMT2A (0.68) | PTGS1ALOX5KMT2ASMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL7155393 | 0.81 | KMT2A (0.68) | PTGS1ALOX5KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8514631 | 0.81 | AOC3 (0.55) | ALDH1A1TSHR | |
| SCHEMBL18793771 | 0.81 | AOC3 (0.55) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |