Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615597 | 0.84 | PTGS1 (0.45) | BRD4CYP2A13CA12ALDH1A1TSHR | |
| Clomazone SCHEMBL6280248 | 0.82 | BRD4 (0.53) | BRD4CYP2A13ALDH1A1TSHRKMT2A | |
| SCHEMBL11194069 | 0.82 | PIM1 (0.44) | BRD4CYP2A13CA12ALDH1A1TSHR | |
| SCHEMBL25072255 | 0.82 | BRD4 (0.43) | BRD4ALDH1A1TSHRKMT2AMEN1 | |
| Clomazone SCHEMBL21816605 | 0.81 | BRD4 (0.52) | BRD4CYP2A13ALDH1A1TSHRKMT2A | |
| Clomazone SCHEMBL27601346 | 0.81 | BRD4 (0.52) | BRD4CYP2A13ALDH1A1TSHRKMT2A | |
| Clomazone SCHEMBL27782874 | 0.81 | BRD4 (0.52) | BRD4CYP2A13ALDH1A1TSHRKMT2A | |
| Clomazone SCHEMBL20723900 | 0.81 | BRD4 (0.52) | BRD4CYP2A13ALDH1A1TSHRKMT2A | |
| SCHEMBL25072256 | 0.81 | BRD4 (0.47) | BRD4TSHRKMT2AMEN1HTT | |
| SCHEMBL11193050 | 0.81 | BRD4 (0.42) | BRD4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405357-A | Herbicidal 3-isoxazolidinones and hydroxamic acids | FMC CORPORATION (US) | 1983-09-20 | — | — | US | claimed |
| EP-1143941-A3 | USE OF 3-ISOXAZOLIDINONES AND HYDROXYLAMINE ACIDS FOR THE TREATMENT OF INFECTIONS | Jomaa Pharmaka GmbH (DE) | 2002-02-06 | — | — | EP | disclosed |
| EP-1143941-A2 | USE OF 3-ISOXAZOLIDINONES AND HYDROXYLAMINE ACIDS FOR THE TREATMENT OF INFECTIONS | Jomaa Pharmaka GmbH (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000041473-A2 | USE OF 3-ISOXAZOLIDINONES AND HYDROXYLAMINE ACIDS FOR THE TREATMENT OF INFECTIONS | JOMAA PHARMAKA GMBH (DE) | 2000-07-20 | — | — | WO | disclosed |
| US-5691274-A | PLANT SAFTENING AGENTS FOR HERBICIDES | ZENECA LIMITED (GB) | 1997-11-25 | — | — | US | disclosed |
| US-5527761-A | MIXTURE OF ISOXAZOLIDINONES, DICHLOROACETAMIDES, TRIAZINE, TOLUIDINE AND SULFONYLUREA HERBICIDES | ZENECA LIMITED (GB) | 1996-06-18 | — | — | US | disclosed |
| US-5527762-A | AMIDES OF HALOALKANOIC ACIDS, INCLUDING OXAZOLIDINES AND THIOZOLIDIENS USED AS NON-PHYTOTOXIC ANTIDOTES | ZENECA LIMITED (GB) | 1996-06-18 | — | — | US | disclosed |
| US-5395816-A | Antidoting herbicidal 3-ixoxazolidinone compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-03-07 | — | — | US | disclosed |
| EP-0561970-B1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS | ZENECA INC (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0561970-A1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS. | ZENECA INC (US) | 1993-09-29 | — | — | EP | disclosed |
| WO-1992010095-A1 | ANTIDOTING HERBICIDAL 3-ISOXAZOLIDINONE COMPOUNDS | ZENECA INC. (US) | 1992-06-25 | — | — | WO | disclosed |
| US-4405357-A | Herbicidal 3-isoxazolidinones and hydroxamic acids | FMC CORPORATION (US) | 1983-09-20 | — | — | US | disclosed |