Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 5/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 8/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19018653 | 1.00 | IL6ST (0.52) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL5500880 | 1.00 | IL6ST (0.52) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL5500159 | 0.90 | IL6ST (0.54) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL3962683 | 0.89 | IL6ST (0.49) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL3960159 | 0.89 | IL6ST (0.49) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL20536993 | 0.87 | IL6ST (0.49) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL29589364 | 0.87 | IL6ST (0.49) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL14690910 | 0.87 | IL6ST (0.49) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL3967160 | 0.87 | IL6ST (0.49) | IL6STPPARANAAAIDH1FAAH | |
| SCHEMBL3960613 | 0.87 | IL6ST (0.49) | IL6STPPARANAAAIDH1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144375-A2 | SYNTHESIS OF OLIGOKETIDES | Kosan Biosciences (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000044717-A2 | SYNTHESIS OF OLIGOKETIDES | KOSAN BIOSCIENCES, INC. (US) | 2000-08-03 | — | — | WO | disclosed |