Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6924410 | 0.85 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4HTR2AKDM1A | |
| SCHEMBL1534305 | 0.85 | HTR2A (0.35) | HTR2AKDM1ACYP2D6 | |
| SCHEMBL30402212 | 0.73 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4HTR2AKDM1A | |
| SCHEMBL1267589 | 0.73 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4HTR2ACYP2D6 | |
| SCHEMBL4016333 | 0.73 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4HTR2AKDM1A | |
| SCHEMBL14856038 | 0.73 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4HTR2ACYP2D6 | |
| SCHEMBL19774140 | 0.73 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4HTR2ACYP2D6 | |
| SCHEMBL8251125 | 0.73 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4HTR2AKDM1A | |
| SCHEMBL21694957 | 0.73 | SLC6A2 (0.47) | SLC6A2SLC6A3SLC6A4HTR2AKDM1A | |
| SCHEMBL14857286 | 0.73 | SLC6A2 (0.43) | SLC6A2SLC6A3SLC6A4HTR2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |