Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19253779 | 0.84 | GRIK1 (0.37) | GRIK1GRIK2EP300ALDH1A1 | |
| SCHEMBL30575782 | 0.84 | EP300 (0.55) | EP300 | |
| SCHEMBL27568373 | 0.82 | GRIK1 (0.36) | GRIK1GRIK2EP300ALDH1A1 | |
| SCHEMBL5509271 | 0.81 | — | — | |
| SCHEMBL11375198 | 0.80 | NPSR1 (0.42) | GRIK1GRIK2ALDH1A1 | |
| SCHEMBL11420914 | 0.78 | EP300 (0.48) | GRIK1GRIK2EP300 | |
| SCHEMBL12080812 | 0.78 | HCAR2 (0.44) | GRIK1GRIK2EP300ALDH1A1 | |
| SCHEMBL1498184 | 0.77 | CYP2D6 (0.35) | GRIK1GRIK2ALDH1A1 | |
| SCHEMBL52705 | 0.77 | CYP2D6 (0.35) | GRIK1GRIK2ALDH1A1 | |
| Benzene SCHEMBL28209984 | 0.77 | GRIK1 (0.33) | GRIK1GRIK2EP300ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161459-A1 | INTERPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000047631-A1 | INTERPOLYMERS | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-17 | — | — | WO | disclosed |