Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7798811 | 1.00 | HCRTR1 (0.45) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7920515 | 0.87 | HCRTR1 (0.45) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7920512 | 0.87 | HCRTR1 (0.45) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7798828 | 0.86 | HCRTR1 (0.44) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7798830 | 0.86 | HCRTR1 (0.44) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7794989 | 0.76 | HCRTR1 (0.46) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7794990 | 0.76 | HCRTR1 (0.46) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL7524979 | 0.71 | HCRTR1 (0.51) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL16876530 | 0.71 | HCRTR1 (0.46) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 | |
| SCHEMBL16876533 | 0.71 | HCRTR1 (0.46) | HCRTR1HCRTR2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870763-B1 | Condensed piperidine derivatives used as a nitrogen monoxide synthase inhibitors | ONO PHARMACEUTICAL CO (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-6228866-B1 | ADMINISTERING NITRIC OXIDE SYNTHASE INHIBITOR TO TREAT CANCER AND NERVOUS SYSTEM, BRAIN, KIDNEY, RESPIRATORY SYSTEM, AUTOIMMUNES, SKIN AND MUSCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-05-08 | — | — | US | disclosed |
| US-6110930-A | NITRIC OXIDE SYNTHASE INHIBITOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0870763-A1 | Condensed piperidine derivatives used as a nitrogen monoxide synthase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |