Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167949 | 0.92 | ESR1 (0.52) | ESR1SMN1; SMN2MEN1KMT2APLA2G2A | |
| SCHEMBL4155886 | 0.92 | ESR1 (0.51) | ESR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4151712 | 0.91 | ESR1 (0.51) | ESR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4165406 | 0.89 | ESR1 (0.52) | ESR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4144091 | 0.87 | ESR1 (0.51) | ESR1SMN1; SMN2ALOX5APMEN1KMT2A | |
| SCHEMBL4152278 | 0.87 | EDNRB (0.52) | ESR1SMN1; SMN2MEN1KMT2APLA2G2A | |
| SCHEMBL4146704 | 0.86 | ESR1 (0.53) | ESR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19949588 | 0.86 | ESR1 (0.51) | ESR1 | |
| SCHEMBL12939116 | 0.85 | ESR1 (0.49) | ESR1 | |
| SCHEMBL7837415 | 0.85 | EDNRB (0.45) | ESR1SMN1; SMN2ALOX5APMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010021719-A1 | 2-phenyl-1- [4- (2-aminoethoxy) - benzyl] - indoles as estrogenic agents | WYETH | 2001-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010021719-A1 | 2-phenyl-1- [4- (2-aminoethoxy) - benzyl] - indoles as estrogenic agents | ESR1, ESR2, GPER1 | ESR1 1/4885SMN1; SMN2 4700/4885GPR34 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.