Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PRNP | P04156 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | APAF1 | O14727 | 2/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1393656 | 0.97 | RXFP1 (0.39) | RXFP1HTR6PKMPRNPCYP1A2 | |
| SCHEMBL3440573 | 0.82 | PARP1 (0.43) | RXFP1PRNPPLAUPARP1KMT2A | |
| SCHEMBL30710586 | 0.81 | RXFP1 (0.48) | RXFP1HTR6PKMPRNPCYP1A2 | |
| SCHEMBL331123 | 0.81 | CYP2A6 (0.39) | CYP1A2ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29429114 | 0.81 | RXFP1 (0.48) | RXFP1HTR6PKMPRNPCYP1A2 | |
| SCHEMBL198796 | 0.81 | RXFP1 (0.48) | RXFP1HTR6PKMPRNPCYP1A2 | |
| SCHEMBL29649174 | 0.81 | CYP2A6 (0.39) | CYP1A2ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL13632075 | 0.73 | CYP1A2 (0.47) | RXFP1HTR6PKMPRNPCYP1A2 | |
| SCHEMBL13631978 | 0.73 | CYP1A2 (0.47) | RXFP1HTR6PKMPRNPCYP1A2 | |
| SCHEMBL30052553 | 0.73 | CYP1A2 (0.47) | RXFP1HTR6PKMPRNPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027353-A4 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-1027353-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| WO-1999018107-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 1999-04-15 | — | — | WO | disclosed |