Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799832 | 0.81 | CHRM2 (0.35) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL21722696 | 0.75 | — | — | |
| SCHEMBL2325783 | 0.74 | CHRM2 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL2326051 | 0.74 | CHRM2 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL2325790 | 0.74 | CHRM2 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL2325787 | 0.74 | CHRM2 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL7334201 | 0.74 | CHRM2 (0.44) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL263415 | 0.73 | CHRM2 (0.36) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL2543856 | 0.73 | CHRM2 (0.36) | CHRM2CHRM1CHRM4CHRM3CHRM5 | |
| SCHEMBL2642444 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796248-B1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | WESTERN THERAPEUTICS INST D (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-6143763-A | Carbostyril derivatives | D. WESTERN THERAPEUTICS INSTITIUTE (JP) | 2000-11-07 | — | — | US | disclosed |
| CN-1172478-A | Quinolone derivative antithrombotic agent | OTSUKA PHARMA CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |
| EP-0796248-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| WO-1997012869-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-10 | — | — | WO | disclosed |