Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.54 |
| ▸ | KDM1A | O60341 | 5/20 | 0.41 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795155 | 0.83 | HDAC6 (0.53) | HDAC6KDM1AWDR91PRMT5WDR77 | |
| SCHEMBL7798197 | 0.77 | HDAC6 (0.53) | HDAC6KDM1AWDR91ALDH1A1POLB | |
| SCHEMBL1174044 | 0.76 | HDAC6 (0.56) | HDAC6KDM1AALDH1A1POLBPKM | |
| SCHEMBL1174010 | 0.74 | HDAC6 (0.55) | HDAC6KDM1APRMT5WDR77ALDH1A1 | |
| SCHEMBL12869052 | 0.74 | HDAC6 (0.60) | HDAC6KDM1APRMT5WDR77ALDH1A1 | |
| SCHEMBL1174426 | 0.73 | HDAC6 (0.56) | HDAC6KDM1AWDR91PRMT5WDR77 | |
| SCHEMBL1174330 | 0.73 | HDAC6 (0.55) | HDAC6KDM1APRMT5WDR77ALDH1A1 | |
| SCHEMBL1173819 | 0.72 | HDAC6 (0.54) | HDAC6KDM1AWDR91PRMT5WDR77 | |
| SCHEMBL1174246 | 0.71 | HDAC6 (1.00) | HDAC6KDM1AWDR91HDAC8ALDH1A1 | |
| SCHEMBL7797376 | 0.71 | HDAC6 (0.55) | HDAC6KDM1AWDR91PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151317-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-12-29 | — | — | WO | disclosed |