Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16218325 | 0.86 | KMT2A (0.52) | KMT2AMDM2SLC6A1SLC6A11GAA | |
| SCHEMBL16353568 | 0.86 | KMT2A (0.49) | KMT2AMDM2SLC6A1SLC6A11GAA | |
| SCHEMBL20371116 | 0.85 | KMT2A (0.44) | KMT2AMDM2GAAMDM4TP53 | |
| SCHEMBL4557334 | 0.85 | KMT2A (0.56) | KMT2AMDM4TP53FABP5 | |
| SCHEMBL13671093 | 0.85 | KMT2A (0.56) | KMT2AMDM4TP53FABP5 | |
| SCHEMBL8843737 | 0.85 | KMT2A (0.52) | KMT2AMDM2MDM4TP53 | |
| SCHEMBL13485373 | 0.85 | KMT2A (0.50) | KMT2AMDM2SLC6A1SLC6A11MDM4 | |
| SCHEMBL21901416 | 0.84 | KMT2A (0.47) | KMT2AMDM2GAAMDM4TP53 | |
| SCHEMBL3423921 | 0.84 | KMT2A (0.46) | KMT2AMDM2MDM4TP53 | |
| SCHEMBL889833 | 0.84 | KMT2A (0.46) | KMT2AMDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0739898-B1 | Phosphonomonoester nucleic acids, methods for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| US-6127346-A | FOR THE TREATMENT OF VIRUSES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-5874553-A | ANTIBODIES; INHIBITOR OF GENE EXPRESSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |
| EP-0739898-A2 | Phosphonomonoester nucleic acids, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-10-30 | — | — | EP | disclosed |