Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 5/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | MC5R | P33032 | 1/20 | 0.39 |
| ▸ | MC3R | P41968 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Ornithine SCHEMBL7800374 | 0.99 | GSR (0.47) | GSRGRIK1GRIK2MMP2MMP9 | |
| Ornithine SCHEMBL7798268 | 0.99 | GSR (0.47) | GSRGRIK1GRIK2MMP2MMP9 | |
| Ornithine Aketoglutarate SCHEMBL8035700 | 0.97 | GSR (0.49) | GSRGRIK1GRIK2MMP2MMP9 | |
| Ornithine SCHEMBL8035721 | 0.97 | GSR (0.49) | GSRGRIK1GRIK2MMP2MMP9 | |
| Lysine SCHEMBL7800516 | 0.96 | GSR (0.53) | GSRGRIK1GRIK2MMP2MMP9 | |
| Ornithine SCHEMBL7797973 | 0.95 | GRIK1 (0.44) | GSRGRIK1GRIK2MMP2MMP9 | |
| D-Ornithine SCHEMBL7801481 | 0.95 | GRIK1 (0.44) | GSRGRIK1GRIK2MMP2MMP9 | |
| Ornithine SCHEMBL7792568 | 0.95 | GRIK1 (0.44) | GSRGRIK1GRIK2MMP2MMP9 | |
| Lysine SCHEMBL7792271 | 0.95 | GSR (0.54) | GSRGRIK1GRIK2MMP2MMP9 | |
| Lysine SCHEMBL7801504 | 0.95 | GSR (0.54) | GSRGRIK1GRIK2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |