Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7801535

C=CC(=O)CC=O.N

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9812717 0.97
SCHEMBL175817 0.75
SCHEMBL1292866 0.71
SCHEMBL29647937 0.71
SCHEMBL290398 0.70
SCHEMBL3630246 0.69
SCHEMBL3760216 0.69
SCHEMBL4205332 0.69
SCHEMBL3629050 0.67 TSHR (0.56)
SCHEMBL32675679 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764638-B1 A process for the preparation of pyridine DAICEL CHEM (JP) 2001-04-18 EP disclosed
US-5952258-A CONDENSATION OF ALIPHATIC ALDEHYDES AND/OR KETONES WITH AMMONIA IN THE PRESENCE OF CATALYSTS CONSISTING OF AT LEAST ONE METAL COMPOUND OR IONS SELECTED FROM INDIUM, SILVER, GERMANIUM, GALLIUM, IN OR ON A ZEOLITE DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1999-09-14 US disclosed
EP-0764638-A1 A process for the preparation of pyridine DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1997-03-26 EP disclosed