Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 9/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornithine SCHEMBL7800082 | 0.99 | SLC1A5 (0.41) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| Ornithine Aketoglutarate SCHEMBL7800084 | 0.99 | SLC1A5 (0.41) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| Lysine SCHEMBL7792825 | 0.97 | SLC1A5 (0.40) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| Lysine SCHEMBL7798547 | 0.97 | SLC1A5 (0.40) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| Ornithine SCHEMBL7798222 | 0.96 | SLC1A5 (0.40) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| Lysine SCHEMBL7802117 | 0.96 | SLC1A5 (0.41) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| Lysine SCHEMBL7800225 | 0.96 | SLC1A5 (0.41) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| Lysine SCHEMBL7802115 | 0.96 | SLC1A5 (0.41) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| Lysine SCHEMBL7793023 | 0.94 | SLC1A5 (0.39) | SLC1A5GRIK1GRIK2GRIK3KDM4E | |
| SCHEMBL7798158 | 0.93 | SLC1A5 (0.43) | SLC1A5GRIK1GRIK2GRIK3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |