Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.85 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.81 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.65 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801642 | 0.97 | GPBAR1 (0.81) | GPBAR1CYSLTR1 | |
| SCHEMBL421067 | 0.92 | GPBAR1 (1.00) | GPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL9581618 | 0.90 | GPBAR1 (0.97) | GPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL9581634 | 0.90 | GPBAR1 (0.97) | GPBAR1CYSLTR1CYSLTR2PDE10A | |
| SCHEMBL8736537 | 0.90 | CYSLTR1 (0.82) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL422355 | 0.89 | CYSLTR1 (1.00) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL30444017 | 0.89 | CYSLTR1 (1.00) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL26632676 | 0.88 | GPBAR1 (0.92) | GPBAR1CYSLTR1CYSLTR2PDE10A | |
| Hydrochloric Acid SCHEMBL7006935 | 0.88 | CYSLTR1 (0.97) | GPBAR1CYSLTR1CYSLTR2 | |
| SCHEMBL9023100 | 0.88 | CYSLTR1 (0.78) | GPBAR1CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775133-B1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2001-05-30 | — | — | EP | disclosed |
| EP-0775133-A1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004267-A1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |