Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.81 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801727 | 0.93 | CYSLTR1 (0.75) | CYSLTR1 | |
| SCHEMBL7806937 | 0.90 | CYSLTR1 (0.66) | CYSLTR1CYSLTR2 | |
| SCHEMBL7810128 | 0.90 | CYSLTR1 (1.00) | CYSLTR1 | |
| SCHEMBL7809951 | 0.86 | CYSLTR1 (0.80) | CYSLTR1 | |
| SCHEMBL7801879 | 0.85 | CYSLTR1 (0.85) | CYSLTR1 | |
| SCHEMBL7808464 | 0.85 | CYSLTR1 (0.78) | CYSLTR1 | |
| SCHEMBL7806848 | 0.84 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2FFAR1AKR1B1 | |
| SCHEMBL7809882 | 0.84 | CYSLTR1 (0.76) | CYSLTR1 | |
| SCHEMBL7810121 | 0.83 | CYSLTR1 (1.00) | CYSLTR1CYSLTR2 | |
| SCHEMBL7807010 | 0.83 | CYSLTR1 (0.61) | CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775133-B1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2001-05-30 | — | — | EP | claimed |
| EP-0775133-A1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-05-28 | — | — | EP | claimed |
| WO-1996004267-A1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | claimed |
| EP-0775133-B1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | MENARINI LAB (ES) | 2001-05-30 | — | — | EP | disclosed |
| WO-1996004267-A1 | NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |