Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805452 | 1.00 | KMT2A (0.43) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7780541 | 0.91 | KMT2A (0.44) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7795354 | 0.91 | KMT2A (0.40) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7780576 | 0.91 | KMT2A (0.40) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7802013 | 0.91 | KMT2A (0.40) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7795396 | 0.90 | KMT2A (0.40) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7801297 | 0.90 | KMT2A (0.40) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7802211 | 0.90 | KMT2A (0.40) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7780348 | 0.90 | KMT2A (0.41) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 | |
| SCHEMBL7784909 | 0.90 | KMT2A (0.41) | KMT2AMEN1POLBMAPKAPK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |