Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.73 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 13/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.58 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.58 |
| ▸ | CCKBR | P32239 | 2/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.58 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9670895 | 0.98 | CYP11B1 (0.71) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL6571077 | 0.86 | CYP11B1 (0.65) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL332630 | 0.85 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL25312529 | 0.85 | CYP11B1 (0.73) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL27491722 | 0.85 | CYP11B1 (0.73) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL7156136 | 0.83 | CYP11B1 (0.80) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL10894195 | 0.82 | CYP19A1 (0.55) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL9669708 | 0.81 | CYP11B1 (0.67) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL6569908 | 0.81 | CYP11B1 (0.61) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 | |
| SCHEMBL12199510 | 0.80 | CYP11B1 (0.89) | CYP11B1CYP11B2CYP19A1CYP3A4NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11059795-B2 | Androgen receptor modulators and methods for their use | ESSA PHARMA, INC. (CA) | 2021-07-13 | — | — | US | disclosed |
| US-20200247763-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | PROVINCIAL HEALTH SERVICES AUTHORITY (CA) | 2020-08-06 | — | — | US | disclosed |
| CN-1097052-C | Process for prodn. of amidinoindole derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 2002-12-25 | — | — | CN | disclosed |
| CN-1067998-C | Hydrate for medicinal use | DAIICHI PHARMACEUDTICAL CO LTD (JP) | 2001-07-04 | — | — | CN | disclosed |
| CN-1062865-C | Process for production of amidinobenzofuran and amidionbenzothiophen derivatives and salt thereof | DAIICHI SEIYAKU CO (JP) | 2001-03-07 | — | — | CN | disclosed |
| EP-0792879-B1 | Process for preparing 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate | DAIICHI SEIYAKU CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| CN-1049654-C | Piperazine derivatives | DAIICHI SEIYAKU CO (JP) | 2000-02-23 | — | — | CN | disclosed |
| CN-1049434-C | Aromatic amidine derivatives and pharmaceutically acceptable salts thereof | DAIICHI SEIYAKU CO (JP) | 2000-02-16 | — | — | CN | disclosed |
| CN-1049219-C | Fused heteroaromatic cyclopentene derivative having endothelin-antagonist activity | BANYU PHARMA CO LTD (JP) | 2000-02-09 | — | — | CN | disclosed |
| CN-1171786-A | Hydrate for medicinal use | DAIICHI SEIYAKU CO (JP) | 1998-01-28 | — | — | CN | disclosed |
| CN-1168886-A | Process for production of amidinobenzofuran and amidionbenzothiophen derivatives and salt thereof | DAIICHI SEIYAKU CO (JP) | 1997-12-31 | — | — | CN | disclosed |
| CN-1168885-A | Process for prodn. of amidinoindole derivatives and salts thereof | DAIICHI SEIYAKU CO (JP) | 1997-12-31 | — | — | CN | disclosed |
| CN-1129448-A | Fused heteroaromatic cyclopentene derivative having endothelin-antagonist activity | BANYU PHARMA CO LTD (JP) | 1996-08-21 | — | — | CN | disclosed |
| CN-1101039-A | Piperazine derivatives | DAIICHI SEIYAKU CO (JP) | 1995-04-05 | — | — | CN | disclosed |
| CN-1072677-A | Aromatic amidine derivative and salt thereof | DAIICHI SEIYAKU CO (JP) | 1993-06-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247763-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS FOR THEIR USE | AR, NR5A1, CYP17A1 | CYP11B1 9/4885CYP11B2 11/4885CYP19A1 15/4885 |
| US-11059795-B2 | Androgen receptor modulators and methods for their use | AR, NR5A1, CYP17A1 | CYP11B1 9/4885CYP11B2 11/4885CYP19A1 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.