Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.83 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.83 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.83 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.83 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.83 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.83 |
| ▸ | EGFR | P00533 | 2/20 | 0.83 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.83 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.80 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.80 |
| ▸ | CSNK1A1 | P48729 | 3/20 | 0.80 |
| ▸ | MINK1 | Q8N4C8 | 3/20 | 0.80 |
| ▸ | MAP4K5 | Q9Y4K4 | 3/20 | 0.80 |
| ▸ | LCK | P06239 | 2/20 | 0.80 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.80 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.80 |
| ▸ | PRKACA | P17612 | 2/20 | 0.80 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.80 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.80 |
| ▸ | PRKCG | P05129 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550753 | 0.95 | MAPK14 (0.91) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL29842083 | 0.92 | MAPK14 (0.98) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL20550893 | 0.92 | MAPK14 (0.98) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL20550876 | 0.92 | MAPK14 (0.93) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL20550488 | 0.91 | MAPK14 (1.00) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL12280165 | 0.91 | MAPK14 (1.00) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL29453495 | 0.91 | MAPK14 (1.00) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL4912960 | 0.90 | MAPK14 (1.00) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL20550765 | 0.90 | MAPK14 (0.98) | MAPK14CSNK1DMAPK13MAPK12MAPK11 | |
| SCHEMBL4916878 | 0.90 | MAPK14 (0.82) | MAPK14CSNK1DMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802908-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2001-04-11 | — | — | EP | disclosed |
| EP-0802908-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021654-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-18 | — | — | WO | disclosed |