Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8130165 | 0.98 | CYP19A1 (0.41) | CYP19A1TAAR1MTORADKNISCH | |
| SCHEMBL6571082 | 0.87 | CYP19A1 (0.39) | CYP19A1TAAR1MTORADKNISCH | |
| Trityl Imidazole SCHEMBL1572623 | 0.85 | MTOR (0.45) | CYP19A1TAAR1MTORADKNISCH | |
| SCHEMBL15263039 | 0.83 | CYP19A1 (0.61) | CYP19A1TAAR1MTORADKNISCH | |
| SCHEMBL11089506 | 0.82 | MTOR (0.45) | CYP19A1TAAR1MTORADKNISCH | |
| SCHEMBL10894207 | 0.82 | TAAR1 (0.35) | CYP19A1TAAR1 | |
| SCHEMBL9669719 | 0.81 | TAAR1 (0.36) | CYP19A1TAAR1MTORADKNISCH | |
| SCHEMBL6569913 | 0.81 | CYP19A1 (0.37) | CYP19A1TAAR1MTORADKNISCH | |
| SCHEMBL1484199 | 0.80 | CYP19A1 (0.41) | CYP19A1TAAR1MTORADKNISCH | |
| SCHEMBL3827055 | 0.80 | CYP19A1 (0.41) | CYP19A1TAAR1MTORADKNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792879-B1 | Process for preparing 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate | DAIICHI SEIYAKU CO (JP) | 2001-02-28 | — | — | EP | disclosed |