Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297277 | 0.86 | CYP3A4 (0.40) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3297273 | 0.86 | CYP3A4 (0.40) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3296818 | 0.86 | CYP3A4 (0.40) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3299151 | 0.86 | CYP3A4 (0.40) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3294268 | 0.86 | CYP3A4 (0.40) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3294270 | 0.86 | CYP3A4 (0.40) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3296410 | 0.81 | CYP3A4 (0.39) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3296408 | 0.81 | CYP3A4 (0.39) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3297031 | 0.81 | CYP3A4 (0.39) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 | |
| SCHEMBL3299779 | 0.80 | CYP3A4 (0.40) | CYP3A4CYP3A5CHRM2ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010027193-A1 | Azetidine derivatives, their preparation and pharmaceutical compositions containing them | AVENTIS PHARMA S.A. (FR) | 2001-10-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010027193-A1 | Azetidine derivatives, their preparation and pharmaceutical compositions containing them | ALK, CYP2C9, CBR1 | CYP3A4 38/4885CYP3A5 29/4885CHRM2 107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.