⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413992 | 0.91 | — | — | |
| SCHEMBL23533 | 0.84 | — | — | |
| SCHEMBL519086 | 0.79 | — | — | |
| SCHEMBL11866314 | 0.75 | — | — | |
| SCHEMBL11866309 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL7715636 | 0.73 | — | — | |
| SCHEMBL237047 | 0.71 | — | — | |
| SCHEMBL9421 | 0.67 | — | — | |
| SCHEMBL519615 | 0.67 | — | — | |
| SCHEMBL13739220 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3021847-B1 | SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| US-RE48992-E1 | Spiroquinoxaline derivatives as inhibitors of non-apoptotic regulated cell-death | HELMHOLTZ ZENTRUM MÜNCHEN-DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2022-03-29 | — | — | US | disclosed |
| US-20210363172-A1 | 5'-CAP-TRINUCLEOTIDE- OR HIGHER OLIGONUCLEOTIDE COMPOUNDS AND THEIR USE IN STABILIZING RNA, EXPRESSING PROTEINS IN THERAPY | BIONTECH RNA PHARMACEUTICALS GMBH (DE) | 2021-11-25 | — | — | US | disclosed |
| US-20210340170-A1 | 5'-CAP COMPOUNDS AND THEIR USES IN STABILIZING RNA, EXPRESSING PROTEINS AND IN THERAPY | BIONTECH RNA PHARMACEUTICALS GMBH (DE) | 2021-11-04 | — | — | US | disclosed |
| EP-3280705-B1 | PYRONE DERIVATIVES FOR USE AS ANTIVIRAL AGENTS | HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) | 2021-07-21 | — | — | EP | disclosed |
| CN-105611930-B | Spiro quinoxaline derivatives as non-apoptotic regulated cell death inhibitors | 亥姆霍兹慕尼黑中心-德国环境与健康研究中心（股份有限公司） | 2021-03-02 | — | — | CN | disclosed |
| EP-3765477-A1 | 5'-CAP-TRINUCLEOTIDE- OR HIGHER OLIGONUCLEOTIDE COMPOUNDS AND THEIR USES IN STABILIZING RNA, EXPRESSING PROTEINS AND IN THERAPY | BioNTech RNA Pharmaceuticals GmbH (DE) | 2021-01-20 | — | — | EP | disclosed |
| CN-112119084-A | 5' -cap trinucleotide or higher oligonucleotide compounds and their use in RNA stabilization, protein expression and therapy | 生物技术RNA制药有限公司 | 2020-12-22 | — | — | CN | disclosed |
| US-10647687-B2 | Spiropyrazine derivatives as inhibitors of non-apoptotic regulated cell-death | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2020-05-12 | — | — | US | disclosed |
| US-10568852-B2 | Combination compositions and their use in methods for treating obesity and obesity-related disorders | HELMHOLTZ ZENTRUM MUNCHEN - DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2020-02-25 | — | — | US | disclosed |
| US-6054413-A | AGRICULTURE, HORTICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |
| US-6054412-A | AGRICULTURE, HORTICULTURE | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |
| CN-1244865-A | Substituted pyrazole-3-yl benzazoles | BASF AK (DE) | 2000-02-16 | — | — | CN | disclosed |
| WO-1999055702-A1 | SUBSTITUTED (4-BROMPYRAZOLE-3-YL)BENZAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999031091-A1 | HERBICIDES 3-(BENZAZOL-4-YL)PYRIMIDINE-DIONE-DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999007702-A1 | SUBSTITUTED HERBICIDE TETRAZOLINONECARBOXYLIC ACID AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-18 | — | — | WO | disclosed |
| WO-1999006394-A1 | SUBSTITUTED 2-(BENZOARYL)PYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1999-02-11 | — | — | WO | disclosed |
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| EP-0879239-A1 | SUBSTITUTED AROMATIC PHOSPHONIC ACID DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1998-11-25 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |