SCHEMBL7803840

SCHEMBL7803840

COC=C(Oc1cccc(C)c1C(=O)O)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
TRPM4 Q8TD43 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ATM Q13315 1/20 0.35
KDM4E B2RXH2 3/20 0.35
HPGD P15428 2/20 0.35
HSD17B10 Q99714 2/20 0.35
ALDH1A1 P00352 2/20 0.34
EDNRA P25101 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.34
TAS1R1 Q7RTX1 1/20 0.34
TAS1R2 Q8TE23 1/20 0.34
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803838 1.00 CA12 (0.42) CA12CA1CA2CA7CA9
SCHEMBL7754517 0.91 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL7795814 0.91 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL7754513 0.91 CA12 (0.51) CA12CA1CA2CA7CA9
SCHEMBL7801818 0.85 POLB (0.42) CA12CA1CA2CA7CA9
SCHEMBL7803904 0.85 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL7795760 0.85 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL7801816 0.85 POLB (0.42) CA12CA1CA2CA7CA9
SCHEMBL7795765 0.85 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL7803906 0.85 CA12 (0.41) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1097117-A2 ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES AVENTIS AGRICULTURE LTD. (GB) 2001-05-09 EP disclosed
WO-2000003975-A2 ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES AVENTIS AGRICULTURE LTD. (GB) 2000-01-27 WO disclosed