Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631950 | 0.87 | MEN1 (0.44) | NPC1 | |
| SCHEMBL321202 | 0.82 | — | — | |
| SCHEMBL330971 | 0.82 | — | — | |
| SCHEMBL28340591 | 0.82 | NPC1 (0.32) | NPC1 | |
| SCHEMBL220922 | 0.82 | TSHR (0.37) | NPC1 | |
| SCHEMBL499569 | 0.82 | — | — | |
| SCHEMBL7799831 | 0.81 | NPC1 (0.33) | NPC1 | |
| SCHEMBL9275152 | 0.80 | NPC1 (0.35) | NPC1 | |
| SCHEMBL10049953 | 0.80 | NPC1 (0.35) | NPC1 | |
| SCHEMBL9275162 | 0.80 | NPC1 (0.35) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0796248-B1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | WESTERN THERAPEUTICS INST D (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-6143763-A | Carbostyril derivatives | D. WESTERN THERAPEUTICS INSTITIUTE (JP) | 2000-11-07 | — | — | US | disclosed |
| CN-1172478-A | Quinolone derivative antithrombotic agent | OTSUKA PHARMA CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |
| EP-0796248-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-24 | — | — | EP | disclosed |
| WO-1997012869-A1 | CARBOSTYRIL DERIVATIVES AS ANTITHROMBOTIC AGENTS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-10 | — | — | WO | disclosed |