Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 6/20 | 0.56 |
| ▸ | HTR1B | P28222 | 6/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8035337 | 0.99 | HTR1D (0.55) | HTR1DHTR1BSLC6A2SLC6A4KCNH2 | |
| SCHEMBL7805932 | 0.86 | HTR1D (0.54) | HTR1DHTR1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL8031488 | 0.85 | HTR1D (0.53) | HTR1DHTR1BSIGMAR1 | |
| SCHEMBL7798270 | 0.82 | HTR1D (0.50) | HTR1DHTR1B | |
| SCHEMBL7807144 | 0.82 | HTR1D (0.56) | HTR1DHTR1BSLC6A2SLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL8033570 | 0.81 | HTR1D (0.55) | HTR1DHTR1BSLC6A2SLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL8033522 | 0.81 | HTR1D (0.49) | HTR1DHTR1B | |
| SCHEMBL7804160 | 0.80 | HTR1D (0.56) | HTR1DHTR1BSLC6A2SLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL8032981 | 0.79 | HTR1D (0.55) | HTR1DHTR1BSLC6A2SLC6A4KCNH2 | |
| SCHEMBL7798221 | 0.75 | HTR1D (0.55) | HTR1DHTR1BSLC6A2SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |