Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 16/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804196 | 1.00 | PTPN1 (0.42) | PTPN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7184852 | 0.89 | PTPN1 (0.51) | PTPN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7184855 | 0.89 | PTPN1 (0.51) | PTPN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7192250 | 0.88 | PTPN1 (0.43) | PTPN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7192244 | 0.88 | PTPN1 (0.43) | PTPN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7187866 | 0.87 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL7187869 | 0.87 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DABCG2 | |
| SCHEMBL7186019 | 0.86 | PTPN1 (0.42) | PTPN1 | |
| SCHEMBL7179701 | 0.86 | PTPN1 (0.46) | PTPN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7186016 | 0.86 | PTPN1 (0.42) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |