Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | NAMPT | P43490 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7813666 | 0.93 | PPARG (0.52) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7810037 | 0.91 | PPARG (0.50) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7813392 | 0.91 | NAMPT (0.50) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7811498 | 0.89 | PPARA (0.47) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7811577 | 0.89 | PPARG (0.49) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7817414 | 0.89 | NAMPT (0.52) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7811760 | 0.89 | PPARG (0.49) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7811630 | 0.89 | PPARA (0.60) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7817648 | 0.89 | PPARG (0.49) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7811694 | 0.89 | PPARG (0.52) | PPARGPPARANAMPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |