Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462043 | 0.89 | TACR2 (1.00) | TACR1TACR2 | |
| SCHEMBL7813792 | 0.88 | TACR1 (0.94) | TACR1TACR2 | |
| SCHEMBL8861327 | 0.87 | TACR1 (0.77) | TACR1TACR2 | |
| SCHEMBL3083325 | 0.86 | TACR2 (1.00) | TACR1TACR2 | |
| SCHEMBL3083322 | 0.86 | TACR2 (1.00) | TACR1TACR2 | |
| SCHEMBL7817312 | 0.86 | TACR1 (0.94) | TACR1TACR2 | |
| SCHEMBL31061161 | 0.85 | TACR1 (1.00) | TACR1TACR2 | |
| SCHEMBL3094798 | 0.85 | TACR1 (1.00) | TACR1TACR2 | |
| SCHEMBL3094790 | 0.85 | TACR1 (1.00) | TACR1TACR2 | |
| SCHEMBL7814154 | 0.84 | TACR1 (1.00) | TACR1TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775132-B1 | (AZETIDIN-1-YLALKYL)LACTAMS AS TACHYKININ ANTAGONISTS | PFIZER LTD (GB) | 2001-03-28 | — | — | EP | disclosed |
| US-5968923-A | ANTIINFLAMMATORY AGENTS, TREATMENT OF NERVOUS SYSTEM DISORDERS, GASTROINTESTINAL DISORDERS | PFIZER INC. (US) | 1999-10-19 | — | — | US | disclosed |
| WO-1996005193-A1 | (AZETIDIN-1-YLALKYL)LACTAMS AS TACHYKININ ANTAGONISTS | PFIZER LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |