Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7806466 | 1.00 | ABCG2 (0.50) | ABCG2PPARAMAOBMAOAPPARG | |
| SCHEMBL7187365 | 0.91 | ABCG2 (0.64) | ABCG2PPARAMAOBMAOAKEAP1 | |
| SCHEMBL7187361 | 0.91 | ABCG2 (0.64) | ABCG2PPARAMAOBMAOAKEAP1 | |
| SCHEMBL7184628 | 0.90 | MAOB (0.50) | ABCG2PPARAMAOBMAOAMAPT | |
| SCHEMBL7184618 | 0.90 | MAOB (0.50) | ABCG2PPARAMAOBMAOAMAPT | |
| SCHEMBL7187237 | 0.88 | ABCG2 (0.47) | ABCG2PPARAMAOBMAOAKEAP1 | |
| SCHEMBL7186013 | 0.88 | ABCG2 (0.48) | ABCG2PPARAMAOBMAOAMAPT | |
| SCHEMBL7187240 | 0.88 | ABCG2 (0.47) | ABCG2PPARAMAOBMAOAKEAP1 | |
| SCHEMBL7184562 | 0.88 | ABCG2 (0.48) | ABCG2PPARAMAOBMAOADPP4 | |
| SCHEMBL7180765 | 0.86 | PPARA (0.39) | ABCG2PPARAMAOBMAOAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| EP-0634927-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1995-01-25 | — | — | EP | disclosed |
| WO-1993017671-A1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | STATENS SERUMINSTITUT (DK) | 1993-09-16 | — | — | WO | disclosed |