Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TERT | O14746 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.32 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819092 | 0.87 | CCR1 (0.48) | CCR1ALDH1A1S1PR4MAPTTERT | |
| SCHEMBL4049786 | 0.84 | S1PR4 (0.36) | ALDH1A1S1PR4MAPTTDP1SLC2A1 | |
| SCHEMBL13739830 | 0.77 | CCR1 (0.39) | CCR1ALDH1A1RAB9AL3MBTL1LMNA | |
| SCHEMBL7245334 | 0.76 | KDM4E (0.55) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| SCHEMBL7245330 | 0.76 | KDM4E (0.55) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| SCHEMBL3748357 | 0.76 | CCR1 (0.48) | CCR1ALDH1A1S1PR4MAPTTERT | |
| SCHEMBL2169969 | 0.76 | CCR1 (0.48) | CCR1ALDH1A1MAPTTERTTDP1 | |
| SCHEMBL1914989 | 0.74 | BACE1 (0.53) | CCR1ALDH1A1TERTNPC1RAB9A | |
| SCHEMBL4052149 | 0.74 | CYP1A2 (0.48) | MAPTKDM4ELMNA | |
| SCHEMBL3597858 | 0.74 | TDP1 (0.48) | CCR1ALDH1A1S1PR4MAPTTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |