Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812320 | 0.79 | ADORA2A (0.48) | ADORA2AADORA1TAAR1ALDH1A1KDM4E | |
| SCHEMBL30417076 | 0.76 | TAAR1 (0.55) | ADORA2AADORA1TAAR1ALDH1A1KDM4E | |
| SCHEMBL7807702 | 0.75 | ADORA2A (0.39) | ADORA2AADORA1TAAR1ALDH1A1KDM4E | |
| SCHEMBL31201127 | 0.74 | PDE10A (0.46) | ADORA2ATAAR1ALDH1A1KDM4EMAPT | |
| SCHEMBL7807613 | 0.74 | MAPT (0.36) | ADORA2AADORA1ALDH1A1KDM4EMAPT | |
| SCHEMBL15695597 | 0.73 | TAAR1 (0.55) | ADORA2AADORA1TAAR1ALDH1A1KDM4E | |
| SCHEMBL7808886 | 0.73 | MAPK1 (0.41) | ADORA2AADORA1TAAR1ALDH1A1KDM4E | |
| SCHEMBL15871996 | 0.72 | TAAR1 (0.54) | TAAR1ALDH1A1KDM4EMAPTBLM | |
| SCHEMBL7807450 | 0.72 | TAAR1 (0.53) | ADORA2AADORA1TAAR1ALDH1A1KDM4E | |
| SCHEMBL22897894 | 0.70 | ADORA2A (0.49) | ADORA2AADORA1TAAR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |