Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | STAT3 | P40763 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | FNTA | P49354 | 1/20 | 0.60 |
| ▸ | FNTB | P49356 | 1/20 | 0.60 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218207 | 1.00 | HRH3 (0.67) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27333111 | 0.90 | HRH3 (0.67) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11189753 | 0.89 | HRH3 (0.67) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18229461 | 0.89 | HRH3 (0.65) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18229442 | 0.89 | HRH3 (0.69) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28374001 | 0.89 | GLA (0.62) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9202235 | 0.87 | CFTR (0.57) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18229439 | 0.86 | HRH3 (0.77) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL25802387 | 0.86 | HRH3 (0.66) | HRH3MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27332104 | 0.86 | MEN1 (0.61) | HRH3MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016181414-A1 | PROCESS FOR THE SYNTHESIS OF IVACAFTOR AND RELATED COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-11-17 | — | — | WO | claimed |
| EP-0754041-A4 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMA (US) | 1997-11-19 | — | — | EP | claimed |
| EP-0754041-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS INCORPORATED (US) | 1997-01-22 | — | — | EP | claimed |
| WO-1995026723-A1 | NOVEL SUBSTITUTED TRYPTAMINES, PHENALKYLAMINES AND RELATED COMPOUNDS | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-10-12 | — | — | WO | claimed |
| US-5403851-A | Central nervous system and psychological disorders | INTERNEURON PHARMACEUTICALS, INC. (US) | 1995-04-04 | — | — | US | claimed |
| CN-111303054-B | 3-acylamino-1, 3-quinazoline-2-ketone compound and preparation method and application thereof | 湖南科技大学 | 2023-04-07 | — | — | CN | disclosed |
| WO-2016181414-A1 | PROCESS FOR THE SYNTHESIS OF IVACAFTOR AND RELATED COMPOUNDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-11-17 | — | — | WO | disclosed |
| EP-0953872-B1 | Photographic element containing improved acylacetamido yellow dye-forming coupler | EASTMAN KODAK CO (US) | 2001-08-22 | — | — | EP | disclosed |
| US-5998107-A | TRIAZINE DERIVATIVE OF A 3-INDOLOACETANILIDE | EASTMAN KODAK COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| EP-0953872-A1 | Photographic element containing improved acylacetamido yellow dye-forming coupler | EASTMAN KODAK COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |