Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809623 | 0.86 | S1PR4 (0.49) | HDAC1HDAC2S1PR4CCR1TDP1 | |
| SCHEMBL2412433 | 0.82 | HDAC1 (0.47) | HDAC1HDAC2FAAHPDE10AHTR3A | |
| SCHEMBL9022559 | 0.81 | PDE10A (0.46) | HDAC1HDAC2FAAHPDE10AHTR3A | |
| SCHEMBL201434 | 0.81 | CCR1 (0.47) | HDAC1HDAC2CCR1TDP1FAAH | |
| SCHEMBL5103462 | 0.81 | HDAC1 (0.46) | HDAC1HDAC2FAAHPDE10AHTR3A | |
| SCHEMBL4720632 | 0.79 | HDAC1 (0.51) | HDAC1HDAC2FAAHPDE10AALDH1A1 | |
| SCHEMBL27529644 | 0.78 | PDE10A (0.47) | HDAC1HDAC2FAAHPDE10AHTR3A | |
| SCHEMBL14127821 | 0.78 | PDE10A (0.50) | HDAC1HDAC2MCHR1FAAHPDE10A | |
| SCHEMBL31434472 | 0.78 | HDAC1 (0.50) | HDAC1HDAC2FAAHPDE10AHTR3A | |
| SCHEMBL12516193 | 0.77 | CCR1 (0.47) | HDAC1HDAC2CCR1MCHR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| CN-1046279-C | Quinoline derivative | UBE INDUSTRIES (JP) | 1999-11-10 | — | — | CN | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |