SCHEMBL7808366

SCHEMBL7808366

CC1(C)c2cc(OC[C@@H](O)CO)ccc2C(=O)c2c1[nH]c1c(Br)c(N)ccc21

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7817988 1.00 ALK (0.69) ALK
SCHEMBL7807837 0.92 ALK (0.72) ALK
SCHEMBL7812139 0.90 ALK (0.70) ALK
SCHEMBL1755901 0.90 ALK (0.78) ALK
SCHEMBL1755902 0.90 ALK (0.70) ALK
SCHEMBL7815272 0.89 ALK (0.72) ALK
SCHEMBL897816 0.88 ALK (0.83) ALK
SCHEMBL897818 0.88 ALK (0.83) ALK
SCHEMBL897819 0.88 ALK (0.83) ALK
SCHEMBL7810444 0.88 ALK (0.80) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010143664-A1 TETRACYCLIC COMPOUND 中外製薬株式会社 (JP) 2010-12-16 WO disclosed