Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 3/20 | 0.31 |
| ▸ | RARB | P10826 | 3/20 | 0.31 |
| ▸ | RARG | P13631 | 2/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100162 | 0.83 | HDAC1 (0.31) | TDP1HDAC1HDAC2HDAC3 | |
| SCHEMBL7800827 | 0.74 | KCNH2 (0.37) | RARARARBRARGHDAC1HDAC2 | |
| SCHEMBL7458242 | 0.72 | — | — | |
| SCHEMBL8060685 | 0.61 | — | — | |
| SCHEMBL7807618 | 0.59 | TDP1 (0.31) | TDP1 | |
| SCHEMBL7805999 | 0.59 | TDP1 (0.43) | TDP1HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL7807514 | 0.58 | NPC1 (0.41) | TDP1HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL7812174 | 0.56 | TDP1 (0.43) | TDP1HDAC1HDAC2HDAC3 | |
| SCHEMBL7809761 | 0.56 | NPC1 (0.40) | TDP1HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL7807264 | 0.56 | AR (0.39) | TDP1HDAC1HDAC2HDAC3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |