SCHEMBL7808540

SCHEMBL7808540

CCN(CCOc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C=N)ccc3c1C2=O)C(=O)OC(C)(C)C

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1755784 0.89 ALK (0.59) ALK
SCHEMBL16775673 0.87 ALK (0.74) ALK
SCHEMBL29961837 0.87 ALK (0.74) ALK
SCHEMBL7808541 0.83 ALK (0.59) ALK
SCHEMBL7811243 0.81 ALK (0.70) ALK
SCHEMBL24675616 0.78 ALK (0.62) ALK
SCHEMBL20366536 0.77 ALK (0.73) ALK
SCHEMBL7806748 0.77 ALK (0.56) ALK
SCHEMBL7802527 0.77 ALK (0.56) ALK
SCHEMBL21443225 0.76 ALK (0.81) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010143664-A1 TETRACYCLIC COMPOUND 中外製薬株式会社 (JP) 2010-12-16 WO disclosed