Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846581 | 0.84 | GAA (0.41) | PDE4DKDM4EMAPTPOLBKMT2A | |
| SCHEMBL353564 | 0.78 | PDE4D (1.00) | PDE4DKDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL10719424 | 0.77 | PDE4D (0.71) | PDE4DKDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL16099449 | 0.75 | PDE4D (0.73) | PDE4DKDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL21130898 | 0.75 | PDE4D (0.73) | PDE4DKDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL7519069 | 0.75 | PDE4D (0.73) | PDE4DKDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL10924357 | 0.75 | CDC7 (0.44) | PDE4DLMNASMN1; SMN2MAPTPOLB | |
| SCHEMBL14812013 | 0.74 | PDE4D (0.67) | PDE4DKDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL19702822 | 0.73 | PDE4D (0.71) | PDE4DKDM4ELMNAPKMSMN1; SMN2 | |
| SCHEMBL9120504 | 0.73 | PDE4D (0.71) | PDE4DKDM4ELMNAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727423-B1 | Process for the preparation of sulfonylurea derivatives and intermediates for this process | LUCKY LTD (KR) | 2001-07-25 | — | — | EP | disclosed |