Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.72 |
| ▸ | HSPA8 | P11142 | 5/20 | 0.44 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.44 |
| ▸ | SLC28A2 | O43868 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7808981 | 1.00 | HDAC6 (0.72) | HDAC6HSPA8HSPA5SLC28A2RXFP1 | |
| SCHEMBL7801019 | 0.89 | HDAC6 (0.72) | HDAC6HSPA8HSPA5SLC28A2RXFP1 | |
| SCHEMBL7801023 | 0.89 | HDAC6 (0.72) | HDAC6HSPA8HSPA5SLC28A2RXFP1 | |
| SCHEMBL7801031 | 0.89 | HDAC6 (0.75) | HDAC6HSPA8HSPA5SLC28A2RXFP1 | |
| SCHEMBL7801027 | 0.89 | HDAC6 (0.75) | HDAC6HSPA8HSPA5SLC28A2RXFP1 | |
| SCHEMBL7807811 | 0.87 | HDAC6 (0.72) | HDAC6HSPA8HSPA5SLC28A2 | |
| SCHEMBL7807814 | 0.87 | HDAC6 (0.72) | HDAC6HSPA8HSPA5SLC28A2 | |
| SCHEMBL7812665 | 0.87 | HDAC6 (0.72) | HDAC6HSPA8HSPA5SLC28A2KDM4E | |
| SCHEMBL7812660 | 0.87 | HDAC6 (0.72) | HDAC6HSPA8HSPA5SLC28A2KDM4E | |
| SCHEMBL7639063 | 0.87 | HDAC6 (0.78) | HDAC6HSPA8HSPA5SLC28A2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307043-B1 | FOR TREATMENT OR PROPHYLAXIS OF HERPES VIRAL INFECTIONS | GLAXO WELLCOME INC. | 2001-10-23 | — | — | US | disclosed |
| US-20010003744-A1 | Therapeutic compounds | CHAMBERLAIN STANLEY DAWES (US) | 2001-06-14 | — | — | US | disclosed |
| US-6077832-A | FOR THERAPY AND PROPHYLAXIS OF HERPES VIRUS INFECTION | GLAXO WELLCOME INC. (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0769017-B1 | THERAPEUTIC COMPOUNDS | WELLCOME FOUND (GB) | 2000-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003744-A1 | Therapeutic compounds | ZC3HAV1, HAVCR2, EIF2AK2 | HDAC6 78/4885HSPA8 2469/4885HSPA5 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.