Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 20/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | SRPK2 | P78362 | 1/20 | 0.43 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.43 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897517 | 0.89 | ALK (0.72) | ALKKDRSRPK2SRPK1EML4 | |
| SCHEMBL7800549 | 0.88 | ALK (0.55) | ALKKDRSRPK2SRPK1EML4 | |
| SCHEMBL7815269 | 0.87 | ALK (0.57) | ALKKDR | |
| SCHEMBL7802442 | 0.85 | ALK (0.58) | ALKKDRSRPK2SRPK1EML4 | |
| SCHEMBL1755929 | 0.85 | ALK (0.59) | ALKKDR | |
| SCHEMBL1755877 | 0.84 | ALK (0.62) | ALKKDRSRPK2SRPK1EML4 | |
| SCHEMBL7808984 | 0.84 | ALK (0.65) | ALKKDR | |
| SCHEMBL7807689 | 0.84 | ALK (0.58) | ALKKDR | |
| SCHEMBL7815503 | 0.83 | ALK (0.78) | ALKKDR | |
| SCHEMBL7813584 | 0.82 | ALK (0.70) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010143664-A1 | TETRACYCLIC COMPOUND | 中外製薬株式会社 (JP) | 2010-12-16 | — | — | WO | disclosed |