Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 5/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025894 | 0.80 | CCNA2 (0.37) | CCNA2CDK2CCNA1 | |
| SCHEMBL7809922 | 0.74 | CDK1 (0.31) | CDK1CCNB1CCNA2CDK2CCNA1 | |
| SCHEMBL7458817 | 0.74 | MGMT (0.51) | TSHRTLR8TLR7CDK1CCNB1 | |
| SCHEMBL8886043 | 0.73 | CDK1 (0.42) | TLR8TLR7CDK1CCNB1CCNA2 | |
| SCHEMBL16462614 | 0.68 | TSHR (0.42) | TSHRTLR8TLR7CDK1CCNB1 | |
| SCHEMBL26978387 | 0.66 | TSHR (0.40) | TSHRTLR8TLR7CDK1CCNB1 | |
| SCHEMBL28870579 | 0.66 | TLR8 (0.42) | TSHRTLR8TLR7CDK1CCNB1 | |
| SCHEMBL30559687 | 0.66 | TSHR (0.40) | TSHRTLR8TLR7CDK1CCNB1 | |
| SCHEMBL16463883 | 0.65 | TSHR (0.39) | TSHRTLR8TLR7CDK1CCNB1 | |
| SCHEMBL7452627 | 0.64 | CDK2 (0.32) | CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675123-B1 | Cyclopropane derivatives and method of preparing the same | AJINOMOTO KK (JP) | 2001-02-21 | — | — | EP | claimed |
| US-5925756-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1999-07-20 | — | — | US | claimed |
| US-5777116-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1998-07-07 | — | — | US | claimed |
| EP-0675123-A1 | Cyclopropane derivatives and method of preparing the same | Ajinomoto Co., Inc. (JP) | 1995-10-04 | — | — | EP | claimed |
| EP-0675123-B1 | Cyclopropane derivatives and method of preparing the same | AJINOMOTO KK (JP) | 2001-02-21 | — | — | EP | disclosed |
| US-5925756-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1999-07-20 | — | — | US | disclosed |
| US-5808134-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5777116-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1998-07-07 | — | — | US | disclosed |
| EP-0433897-B1 | Process for preparing an optically active cyclobutane nucleoside | SQUIBB & SONS INC (US) | 1997-10-01 | — | — | EP | disclosed |
| US-5556994-A | Cyclopropane derivatives and method of preparing the same | AJINOMOTO CO., INC. (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0675123-A1 | Cyclopropane derivatives and method of preparing the same | Ajinomoto Co., Inc. (JP) | 1995-10-04 | — | — | EP | disclosed |
| US-5306837-A | Intermediates for an optically active cyclobutane nucleoside | E. R. SQUIBB & SONS, INC. (US) | 1994-04-26 | — | — | US | disclosed |
| US-5256806-A | Intermediates for the preparation of optically active cyclobutane nucleoside | E. R. SQUIBB & SONS, INC. (US) | 1993-10-26 | — | — | US | disclosed |
| US-5198583-A | Optically active cyclobutane nucleoside and intermediates, therefor | E. R. SQUIBB & SONS, INC. (US) | 1993-03-30 | — | — | US | disclosed |
| US-5064961-A | PROCESS FOR PREPARING AN OPTICALLY ACTIVE CYCLOBUTANE NUCLEOSIDE | E. R. SQUIBB & SONS, INC. (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0433897-A2 | Process for preparing an optically active cyclobutane nucleoside | E.R. SQUIBB & SONS, INC. (US) | 1991-06-26 | — | — | EP | disclosed |